| Sabtu, September 11, 2010 | |||||
| Kandang | Tandang | STADIUN | |||
| Borussia Dortmund | v | VfL Wolfsburg | Signal Iduna Park | ||
| Borussia Monchengladbach | v | Eintracht Frankfurt | Borussia-Park | ||
| Hamburg SV | v | Nurnberg | Imtech Arena | ||
| Hannover 96 | v | Bayer Leverkusen | AWD-Arena | ||
| SC Freiburg | v | VfB Stuttgart | badenova-Stadion | ||
| Bayern Munich | v | Werder Bremen | Allianz Arena | ||
| Minggu, September 12, 2010 | |||||
| Kandang | Tandang | STADIUN | |||
| Mainz | v | Kaiserslautern | Stadion am Bruchweg | ||
| FC Cologne | v | St Pauli | RheinEnergieStadion | ||
| Sabtu, September 18, 2010 | |||||
| Kandang | Tandang | STADIUN | |||
| Bayer Leverkusen | v | Nurnberg | BayArena | ||
| Bayern Munich | v | FC Cologne | Allianz Arena | ||
| Eintracht Frankfurt | v | SC Freiburg | Commerzbank Arena | ||
| Kaiserslautern | v | TSG Hoffenheim | Fritz-Walter-Stadion | ||
| Schalke 04 | v | Borussia Dortmund | Veltins-Arena | ||
| St Pauli | v | Hamburg SV | Millerntor-Stadion | ||
| VfB Stuttgart | v | Borussia Monchengladbach | Mercedes-Benz Arena | ||
| VfL Wolfsburg | v | Hannover 96 | Volkswagen Arena | ||
| Werder Bremen | v | Mainz | Weserstadion | ||
| Selasa, September 21, 2010 | |||||
| Kandang | Tandang | STADIUN | |||
| Bayer Leverkusen | v | Eintracht Frankfurt | BayArena | ||
| Borussia Dortmund | v | Kaiserslautern | Signal Iduna Park | ||
| Borussia Monchengladbach | v | St Pauli | Borussia-Park | ||
| Hamburg SV | v | VfL Wolfsburg | Imtech Arena | ||
| Hannover 96 | v | Werder Bremen | AWD-Arena | ||
| Mainz | v | FC Cologne | Stadion am Bruchweg | ||
| Nurnberg | v | VfB Stuttgart | EasyCredit-Stadion | ||
| SC Freiburg | v | Schalke 04 | badenova-Stadion | ||
| TSG Hoffenheim | v | Bayern Munich | Rhein-Neckar-Arena | ||
| Sabtu, September 25, 2010 | |||||
| Kandang | Tandang | STADIUN | |||
| Bayern Munich | v | Mainz | Allianz Arena | ||
| Eintracht Frankfurt | v | Nurnberg | Commerzbank Arena | ||
| FC Cologne | v | TSG Hoffenheim | RheinEnergieStadion | ||
| Kaiserslautern | v | Hannover 96 | Fritz-Walter-Stadion | ||
| Schalke 04 | v | Borussia Monchengladbach | Veltins-Arena | ||
| St Pauli | v | Borussia Dortmund | Millerntor-Stadion | ||
| VfB Stuttgart | v | Bayer Leverkusen | Mercedes-Benz Arena | ||
| VfL Wolfsburg | v | SC Freiburg | Volkswagen Arena | ||
| Werder Bremen | v | Hamburg SV | Weserstadion | ||